SMALL MOLECULE DRUG DISCOVERY TARGETING THE JAK-STAT PATHWAY

Small molecule drug discovery targeting the JAK-STAT pathway

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway functions as a central hub for transmitting signals from more than 50 cytokines, playing a pivotal role Accessories in maintaining hematopoiesis, immune balance, and tissue homeostasis.Dysregulation of this pathway has been implicated in various diseases, including

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Optimization of packing factor for maximum electric power and crop yield in greenhouse integrated semi-transparent photo-voltaic thermal (GiSPVT) system in desert land: An experimental study

It is well known that food and energy requirement for human Accessories beings is increasing day by day due to the fast increase of population in the world.This can be met by (i) increasing the yield of crop per unit area, (ii) post-harvest losses, and (iii) using the barren land, which is about 19% for crop/vegetable production.The barren land con

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Geographical Discrimination in Curcuminoids Content of Turmeric Assessed by Rapid UPLC-DAD Validated Analytical Method

A fast and reliable ultra-performance liquid chromatography-diode array detection method was developed and validated for the quantitative assessment of turmeric extracts from different geographical locations.Acclaim RSLC PolarAdvantage II column (2.2 μm, 2.1 × 100 mm) was used to analyze individual curcuminoids (curcumin, demethoxycurcumi

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